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AI-powered research assistant — from idea to full paper.

$ curl -fsSL https://raw.githubusercontent.com/XiangJinyu/open-research/main/install.sh | bash

Research Projects

Papers generated with the assistance of Open Research.

First page of Finitude and the Weight of Choice
#04
PhilosophyAI & HumanityEthics

Finitude and the Weight of Choice

A philosophy paper arguing that human uniqueness in the AI era is grounded in finitude rather than simulable cognitive properties. Introduces the concept of 'weight of choice' as a distinguishing feature of embodied, mortal agents.

First page of A Computational Framework for Designing Evolutionary-Robust Multi-Layer Kill Switches in Engineered Bacteria
#08
Synthetic BiologyBiocontainmentComputational Biology

A Computational Framework for Designing Evolutionary-Robust Multi-Layer Kill Switches in Engineered Bacteria

A computational framework modeling six kill switch architectures with mutation-spectrum-decomposed escape rates and stochastic serial passage simulations. Identifies a triple-layer design (CRISPR multi-gRNA + overlapping gene + synthetic auxotrophy) achieving 6.1×10⁻¹⁸ escape rate — ten orders of magnitude below the NIH threshold — at 20% fitness cost.